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sa 11  (ATCC)


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    ATCC sa 11
    Antibiofilm and anti-virulence activity by Nifuratel. (A, B) Biofilm inhibitory activity against ATCC 43300 determination by crystal violet staining (A) and CFU counting assay (B) , respectively. Dotted line indicates limit of detection. (C, D) Pre-formed biofilm eradicating activity against ATCC 43300 determination by crystal violet staining (C) and CFU counting assay (D) , respectively. Dotted line indicates limit of detection. (E, F) Biofilm inhibition (E) and eradication (F) activities detection by SYTO9/PI staining. The concentrations of Nifuratel used for the biofilm inhibitory and eradicating assays were 4 and 8 μg/mL, respectively. (G) Hemolytic activity of MRSA on the sheep blood agars in the presence or absence of 4 μg <t>Nifuratel.</t> <t>SA-11</t> was selected for this assay due to its strong hemolytic activity. (H) Hemolytic activity quantitative of Nifuratel at the concentration of 1/2× MIC. (I) Surface spreading inhibition by sub-MICs of Nifuratel. (J) Auto-aggregation of ATCC 43300 in the presence or absence of 1/2× MIC Nifuratel. * P < 0.05. ** P < 0.01. *** P < 0.001. **** P < 0.0001.
    Sa 11, supplied by ATCC, used in various techniques. Bioz Stars score: 93/100, based on 62 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    sa 11 - by Bioz Stars, 2026-02
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    Images

    1) Product Images from "Drug repurposing of Nifuratel against methicillin-resistant Staphylococcus aureus through proton motive force disruption"

    Article Title: Drug repurposing of Nifuratel against methicillin-resistant Staphylococcus aureus through proton motive force disruption

    Journal: Frontiers in Cellular and Infection Microbiology

    doi: 10.3389/fcimb.2025.1738031

    Antibiofilm and anti-virulence activity by Nifuratel. (A, B) Biofilm inhibitory activity against ATCC 43300 determination by crystal violet staining (A) and CFU counting assay (B) , respectively. Dotted line indicates limit of detection. (C, D) Pre-formed biofilm eradicating activity against ATCC 43300 determination by crystal violet staining (C) and CFU counting assay (D) , respectively. Dotted line indicates limit of detection. (E, F) Biofilm inhibition (E) and eradication (F) activities detection by SYTO9/PI staining. The concentrations of Nifuratel used for the biofilm inhibitory and eradicating assays were 4 and 8 μg/mL, respectively. (G) Hemolytic activity of MRSA on the sheep blood agars in the presence or absence of 4 μg Nifuratel. SA-11 was selected for this assay due to its strong hemolytic activity. (H) Hemolytic activity quantitative of Nifuratel at the concentration of 1/2× MIC. (I) Surface spreading inhibition by sub-MICs of Nifuratel. (J) Auto-aggregation of ATCC 43300 in the presence or absence of 1/2× MIC Nifuratel. * P < 0.05. ** P < 0.01. *** P < 0.001. **** P < 0.0001.
    Figure Legend Snippet: Antibiofilm and anti-virulence activity by Nifuratel. (A, B) Biofilm inhibitory activity against ATCC 43300 determination by crystal violet staining (A) and CFU counting assay (B) , respectively. Dotted line indicates limit of detection. (C, D) Pre-formed biofilm eradicating activity against ATCC 43300 determination by crystal violet staining (C) and CFU counting assay (D) , respectively. Dotted line indicates limit of detection. (E, F) Biofilm inhibition (E) and eradication (F) activities detection by SYTO9/PI staining. The concentrations of Nifuratel used for the biofilm inhibitory and eradicating assays were 4 and 8 μg/mL, respectively. (G) Hemolytic activity of MRSA on the sheep blood agars in the presence or absence of 4 μg Nifuratel. SA-11 was selected for this assay due to its strong hemolytic activity. (H) Hemolytic activity quantitative of Nifuratel at the concentration of 1/2× MIC. (I) Surface spreading inhibition by sub-MICs of Nifuratel. (J) Auto-aggregation of ATCC 43300 in the presence or absence of 1/2× MIC Nifuratel. * P < 0.05. ** P < 0.01. *** P < 0.001. **** P < 0.0001.

    Techniques Used: Activity Assay, Staining, Inhibition, Concentration Assay



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    Image Search Results


    Antibiofilm and anti-virulence activity by Nifuratel. (A, B) Biofilm inhibitory activity against ATCC 43300 determination by crystal violet staining (A) and CFU counting assay (B) , respectively. Dotted line indicates limit of detection. (C, D) Pre-formed biofilm eradicating activity against ATCC 43300 determination by crystal violet staining (C) and CFU counting assay (D) , respectively. Dotted line indicates limit of detection. (E, F) Biofilm inhibition (E) and eradication (F) activities detection by SYTO9/PI staining. The concentrations of Nifuratel used for the biofilm inhibitory and eradicating assays were 4 and 8 μg/mL, respectively. (G) Hemolytic activity of MRSA on the sheep blood agars in the presence or absence of 4 μg Nifuratel. SA-11 was selected for this assay due to its strong hemolytic activity. (H) Hemolytic activity quantitative of Nifuratel at the concentration of 1/2× MIC. (I) Surface spreading inhibition by sub-MICs of Nifuratel. (J) Auto-aggregation of ATCC 43300 in the presence or absence of 1/2× MIC Nifuratel. * P < 0.05. ** P < 0.01. *** P < 0.001. **** P < 0.0001.

    Journal: Frontiers in Cellular and Infection Microbiology

    Article Title: Drug repurposing of Nifuratel against methicillin-resistant Staphylococcus aureus through proton motive force disruption

    doi: 10.3389/fcimb.2025.1738031

    Figure Lengend Snippet: Antibiofilm and anti-virulence activity by Nifuratel. (A, B) Biofilm inhibitory activity against ATCC 43300 determination by crystal violet staining (A) and CFU counting assay (B) , respectively. Dotted line indicates limit of detection. (C, D) Pre-formed biofilm eradicating activity against ATCC 43300 determination by crystal violet staining (C) and CFU counting assay (D) , respectively. Dotted line indicates limit of detection. (E, F) Biofilm inhibition (E) and eradication (F) activities detection by SYTO9/PI staining. The concentrations of Nifuratel used for the biofilm inhibitory and eradicating assays were 4 and 8 μg/mL, respectively. (G) Hemolytic activity of MRSA on the sheep blood agars in the presence or absence of 4 μg Nifuratel. SA-11 was selected for this assay due to its strong hemolytic activity. (H) Hemolytic activity quantitative of Nifuratel at the concentration of 1/2× MIC. (I) Surface spreading inhibition by sub-MICs of Nifuratel. (J) Auto-aggregation of ATCC 43300 in the presence or absence of 1/2× MIC Nifuratel. * P < 0.05. ** P < 0.01. *** P < 0.001. **** P < 0.0001.

    Article Snippet: The low resistance development probability by Nifuratel was also observed by ATCC 25923 and SA-11 ( ).

    Techniques: Activity Assay, Staining, Inhibition, Concentration Assay